发明名称 CHRONIC CARDIAL INSUFFICIENCY COURSE PREDICTION METHOD
摘要 FIELD: medicine. ^ SUBSTANCE: invention refers to cardiology, particularly to prediction of clinical course of chronic cardiac insufficiency. The method is ensured by evaluating whole blood samples for CD133+-cells thereafter analysed for colony-formation ability when cultivated in vitro. Risk of unfavourable outcome, including early death and/or hospitalisation is highest, if examination of the patient suffering from chronic cardiac insufficiency shows representation of CD133+-cells in whole blood is 1ù105/l or less, while colony-formation units are total 2/mm2 or less. The favourable outcome is predicted, if representation of CD133+-cells in whole blood is 1ù105/l or more and number of colony-formation units is 2/mm2 or more. ^ EFFECT: application of the invention allows for high-reliable prediction of unfavourable clinical course of chronic cardiac insufficiency. ^ 5 tbl, 4 ex
申请公布号 RU2357250(C1) 申请公布日期 2009.05.27
申请号 RU20070145813 申请日期 2007.12.10
申请人 FEDERAL'NOE GOSUDARSTVENNOE UCHREZHDENIE "FEDERAL'NYJ TSENTR SERDTSA, KROVI I EHNDOKRINOLOGII IMENIV.A. ALMAZOVA FEDERAL'NOGO AGENTSTVA PO VYSOKOTEKHNOLOGICHNOJ MEDITSINSKOJ POMOSHCHI" 发明人 KARELKINA ELENA VIKTOROVNA;MOISEEVA OL'GA MIKHAJLOVNA
分类号 G01N33/48;G01N33/53 主分类号 G01N33/48
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