发明名称 |
GRANULATE CONTAINING A PHARMACEUTICALLY ACTIVE SUBSTANCE AND AN EMULSIFIER AND METHOD FOR ITS MANUFACTURE |
摘要 |
One aspect of the present invention relates to a granulate having a volume weighted mean diameter of 1-200 m and containing: at least 0.1 wt. % of a pharmaceutically active substance; at least 10 wt. % of emulsifier 0-89.9 wt. % of a water-dispersible saccharide; the combination of the pharmaceutically active substance, the emulsifier and the water-dispersible saccharide together representing at least 60 wt. % of the granulate; wherein the granulate is monophasic or wherein the granulate comprises a dispersed phase containing the pharmaceutically active substance, said dispersed phase having a volume weighted mean diameter of less than 300 nm. Another aspect of the invention relates to a process for the preparation of said granulate containing a pharmaceutically active substance, which process employs. |
申请公布号 |
EP2061427(A2) |
申请公布日期 |
2009.05.27 |
申请号 |
EP20070808579 |
申请日期 |
2007.09.14 |
申请人 |
ECHO PHARMACEUTICALS B.V. |
发明人 |
PELLIKAAN, HUBERT CLEMENS;VERMEULEN, PIETER SEBASTIAAN;BENDER, JOHANNES CASPAR MATHIAS ELIZABETH;FERNANDEZ CID, MARIA VANESA |
分类号 |
A61K9/00;A61K9/16 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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