| 发明名称 |
HUMAN ANTI-FOLATE RECEPTOR ALPHA ANTIBODIES AND ANTIBODY FRAGMENTS FOR THE RADIOIMMUNOTHERAPY OF OVARIAN CARCINOMA |
| 摘要 |
Antibody or fragment thereof, which specifically binds to folate receptor-alpha (FR±), wherein said antibody or fragment thereof comprises a light chain whose variable region comprises at least one of the following amino acid sequences :
- RASESVSFLGINLIH (SEQ ID NO: 3),
- QASNKDT (SEQ ID NO: 4),
- LQSKNFPPYT (SEQ ID NO: 5),
and wherein the constant region of said light chain is a kappa constant region. |
| 申请公布号 |
EP2061813(A1) |
申请公布日期 |
2009.05.27 |
| 申请号 |
EP20070802280 |
申请日期 |
2007.09.12 |
| 申请人 |
DOMPE PHA.R.MA S.P.A.;ISTITUTO NAZIONALE PER LO STUDIO E LA CURA DEI TUMORI |
发明人 |
MARTIN, FRANCK;CATTOZZO, MARGHERITA;MAURIZI, GIOVANNI;DI CIOCCIO, VITO;FIGINI, MARIANGELA;CANEVARI, SILVANA |
| 分类号 |
C07K16/28 |
主分类号 |
C07K16/28 |
| 代理机构 |
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