发明名称 |
17alpha-alkyl-17beta-oxy-estratrienes and intermediate products for their production, use of the 17alpha-alkyl-17beta-oxy-estratrienes for the production of pharmaceutical agents as well as pharmaceutical preparations |
摘要 |
The invention relates to 17alpha-alkyl-17beta-oxy-estra-1,3,5(10)-trienes that have an antiestrogenic action with general formula I. In addition, the invention also relates to 17-oxo-estra-1,3,5(10)-trienes as well as 17beta-hydroxy-estra-1,3,5(10)-trienes as intermediate products in the production of the estratrienes according to the invention. The invention also relates to the use of 17alpha-alkyl-17beta-oxy-estratrienes for the production of pharmaceutical agents as well as pharmaceutical preparations that contain at least one 17alpha-alkyl-17beta-oxy-estratriene as well as at least one pharmaceutically compatible vehicle.
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申请公布号 |
US7538100(B2) |
申请公布日期 |
2009.05.26 |
申请号 |
US20050188992 |
申请日期 |
2005.07.26 |
申请人 |
BAYER SCHERING PHARMA AKTIENGESELLSCHAFT |
发明人 |
BOHLMANN ROLF;HEINRICH NIKOLAUS;JAUTELAT ROLF;KROLL JORG;PETROV ORLIN;REICHEL ANDREAS;HOFFMANN JENS;LICHTNER ROSEMARIE |
分类号 |
A61K31/56;A61K31/567;A61K31/5685;A61K31/569;A61K31/58;A61P5/32;A61P13/08;A61P15/08;A61P15/16;A61P15/18;A61P17/14;A61P35/00;C07J1/00;C07J41/00;C07J43/00 |
主分类号 |
A61K31/56 |
代理机构 |
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地址 |
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