发明名称 Compositions and methods for therapeutic use
摘要 A method and pharmaceutical composition for the enhancement of transfer of a therapeutic agent to a cell wherein the therapeutic agent is formulated in a buffer comprising a compound of Formula I: wherein: n is an integer from 2-8; X1 is a cholic acid group or deoxycholic acid group; and X2 and X3 are each independently selected from the group consisting of a cholic acid group, a deoxycholic acid group, and a saccharide group, wherein the saccharide group is selected from the group consisting of pentose monosaccharide groups, hexose monosaccharide groups, pentose-pentose disaccharide groups, hexose-hexose disaccharide groups, pentose-hexose disaccharide groups, and hexose-pentose disaccharide groups; and wherein at least one of X2 and X3 is a saccharide group.
申请公布号 US7538093(B2) 申请公布日期 2009.05.26
申请号 US20060359997 申请日期 2006.02.21
申请人 SCHERING CORPORATION;CANJI, INC. 发明人 ENGLER HEIDRUN;NAGABHUSHAN TATTANAHALLI L.;YOUNGSTER STEPHEN KENNETH
分类号 A61K31/70;A61K47/26;A61K38/00;A61K47/28;A61K48/00;A61P35/00;A61P43/00;C07J41/00;C07J53/00 主分类号 A61K31/70
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