| 摘要 |
This invention relates to novel compounds, capable of potentiating the efficacy of therapeutically active compounds, for example cytotoxic compound s used in the treatment of cancer. The novel compounds have been shown to increase the pharmacological activity of a conventional paclitaxel formulati on and to make it possible to manufacture a new formulation of paclitaxel, exhibiting improved solubility, improved storage properties, and increased therapeutic efficacy as shown in the enclosed examples. (Formula I, II, III, IV, V, VI)
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