发明名称 |
Amplified and overexpressed gene in colorectal cancers |
摘要 |
This invention relates to methods to diagnose colon cancer and other proliferative diseases. Gene 26#77 is identified herein as a novel oncogene. Methods are provided for diagnosing and treating a disease or disorder characterized by amplification of the 26#77 gene and/or overexpression of 26#77 gene products. The 26#77 gene is located on chromosome 20q13.2, a region whose amplification is associated with a poor cancer prognosis. The 26#77 gene is amplified and 26#77 RNA and protein are overexpressed in 60% of colorectal cancers.
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申请公布号 |
US7537905(B2) |
申请公布日期 |
2009.05.26 |
申请号 |
US20030346367 |
申请日期 |
2003.01.15 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
SLAMON DENNIS J.;ANDERSON LEE A.;GINTHER CHARLES L. |
分类号 |
G01N33/574;C12Q1/68 |
主分类号 |
G01N33/574 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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