| 发明名称 |
CHIMERIC MONOCLONAL ANTIBODY OBTAINED FROM MURINE ANTI-IDIOTYPICMONOCLONAL ANTIBODY 1E10 THAT RECOGNIZES MURINE MABP3 |
| 摘要 |
The invention relates to chimeric monoclonal antibody derived from murine anti-idiotypic monoclonal antibody 1E10 that recognizes murine MAbP3 produced by hybridomas cell line with deposit number ECACC 97112901. Murine MAbP3 specifically binds with gangliosides containing T-glycolilated sialic acid. The invention relates as well to pharmaceutical composition containing disclosed antibody and use of monoclonal antibody for producing medicinal agent useful for treatment of malignant mammary tumors and melanomas, metastases thereof and recurrences. |
| 申请公布号 |
UA86768(C2) |
申请公布日期 |
2009.05.25 |
| 申请号 |
UA20050012270 |
申请日期 |
2005.12.20 |
| 申请人 |
CENTRO DE INMUNOLOGIA MOLECULAR |
发明人 |
LOMBARDERO VALLADARES JOSEFA;ROQUE NAVARRO LOURDES TATIANA;LOPEZ REQUENA ALEJANDRO |
| 分类号 |
C07K16/42;C12N15/09;A61K31/7032;A61K31/739;A61K39/00;A61K39/395;A61P35/00;A61P35/04;A61P37/00;A61P37/04;A61P43/00;C07K16/00;C07K16/18;C07K16/30;C07K16/46;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N5/20;C12N15/13;C12P21/08 |
主分类号 |
C07K16/42 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
