| 摘要 |
An 8-oxoadenine compound represented by the formula (1): [wherein ring A represents a 6-to 10-membered aromatic carbocycle, etc.; R represents halogeno, alkyl, etc.; n is an integer of 0 to 2; Zrepresents alkylene; Xrepresents oxygen, sulfur, SO, NR, CO, CONR, NRCO, etc.; Y, Y, and Yeach independently represents a single bond or alkylene; Xrepresents oxygen, sulfur, NR(wherein Rrepresents hydrogen or alkyl), or a single bond; Rrepresents (un)substituted alkyl, etc.; and Rrepresents hydrogen, hydroxy, alkoxy, alkoxycarbonyl, haloalkyl, etc.] or a pharmaceutically acceptable salt thereof. They have immunoregulatory activity such as interferon-inducing activity and are useful as an antiviral agent, antiallergic, etc.(1) |
