ENRICHED ANTIBODY FOR DETECTING MYCOBACTERIAL INFECTION, METHODS OF USE AND DIAGNOSTIC TEST EMPLOYING SAME

摘要

The disclosed technology provides an enriched antibody population, specific for an surface polysaccharide antigen from a mycobacterium. In a related embodiment, the antibody is enriched by having been raised in an environment that maintains antigenically active antigen. These enriched antibodies may be used in conjunction with an immunoassay, particularly an immunoassay in an ICT format, for detecting the presence of a mycobacterial infection in a sample from a subject, wherein the antibody is selected to be unaffected by the presence of HIV in the sample.