| 摘要 |
<p>The invention relates to compounds, in particular 2-amino- 3, 4, 5, -trisubstituted thiophenes, pharmaceutical compositions containing them and the uses of said compounds and compositions for diseases related to sphingosine-1-phosphate (S1P) receptors, predominantly SlP3 receptors. The diseases include cardiovascular diseases, atherosclerosis, cancer, pulmonary oedema, autoimmune disorders and Adult Respiratory Distress Syndrome.</p> |
| 申请人 |
UNIVERSITEIT LEIDEN;BRUSSEE, JOHANNES;IJZERMAN, ADRIAAN, PIETER;ALEWIJNSE, ASTRID, ELINE;PETERS, STEPHAN, LEONARD MARIA;BEUKERS, MARGOT, WILHELMINA |
发明人 |
BRUSSEE, JOHANNES;IJZERMAN, ADRIAAN, PIETER;ALEWIJNSE, ASTRID, ELINE;PETERS, STEPHAN, LEONARD MARIA;BEUKERS, MARGOT, WILHELMINA |
