摘要 |
<p>The invention provides compounds of formula wherein R1, R3, L1, L2, G1, G2, A and m are as defined in the specification and optical isomers, racemates and tautomers thereof, and pharmaceutically acceptable salts thereof; together with processes for their preparation, pharmaceutical compositions containing them and their use in therapy. The compounds are inhibitors of microsomal prostaglandin E synthase-1.</p> |
申请人 |
ASTRAZENECA AB;BYLUND, JOHAN;EK, MARIA;HOLENZ, JOERG;JOHANSSON, MARTIN H;KERS, ANNIKA;NAERHI, KATJA;NORDVALL, GUNNAR;OEHBERG, LISELOTTE;SOHN, DANIEL;VIKLUND, JENNY;VON BERG, STEFAN |
发明人 |
BYLUND, JOHAN;EK, MARIA;HOLENZ, JOERG;JOHANSSON, MARTIN H;KERS, ANNIKA;NAERHI, KATJA;NORDVALL, GUNNAR;OEHBERG, LISELOTTE;SOHN, DANIEL;VIKLUND, JENNY;VON BERG, STEFAN |