发明名称 |
Monoclonal antibodies that bind to hGM-CSF and medical compositions comprising same |
摘要 |
Disclosed herein are anti-hGM-CSF monoclonal antibodies and antigen-binding fragments of such antibodies, with improved neutralizing capacity to hGM-CSF activity. Pharmaceutical compositions comprising such an antibody or antigen-binding fragment are also provided. The present invention is useful for the treatment of various diseases that are associated with aberrant expression of hGM-CSF. |
申请公布号 |
AU2008321429(A1) |
申请公布日期 |
2009.05.22 |
申请号 |
AU20080321429 |
申请日期 |
2008.11.12 |
申请人 |
BOEHRINGER INGELHEIM INTERNATIONAL GMBH;EVEC INC. |
发明人 |
KENZO TAKADA;KANTOU NAKAJIMA;JOHN PARK;BARBARA KISTLER |
分类号 |
C07K16/24;A61P11/00;A61P17/06;A61P19/02;A61P35/02 |
主分类号 |
C07K16/24 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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