| 发明名称 |
GEF-H1b: biomarkers, complexes, assays and therapeutic uses thereof |
| 摘要 |
The present invention relates to diagnosing abnormal cell proliferation in biological samples and screening for drugs which inhibit, reduce or abolish cell growth, especially tumorigenic cell growth, by detecting a phosphovariant isoform of a guanine nucleotide exchange factor biomarker, such as the novel GEF-H1S.
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| 申请公布号 |
US2009130695(A1) |
申请公布日期 |
2009.05.21 |
| 申请号 |
US20080232134 |
申请日期 |
2008.09.11 |
| 申请人 |
SUGEN, INC. |
发明人 |
SMEAL TOD R.;CALLOW MARINELLA G.;JALLAL BAHIJA;ZOZULYA SERGEY;GISHIZKY MIKHAIL L. |
| 分类号 |
G01N33/50;G01N33/574;A61K38/00;A61K38/55;A61K45/00;A61K48/00;A61P35/00;C07K7/08;C07K14/47;C07K14/82;C07K16/18;C07K16/40;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/12;C12N15/09;C12N15/12;C12Q1/48;G01N33/15;G01N33/53;G01N33/536 |
主分类号 |
G01N33/50 |
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