| 发明名称 |
2-OXO-1-PYRROLIDINE DERIVATIVES, METHOD OF OBTAINMENT |
| 摘要 |
FIELD: chemistry. ^ SUBSTANCE: invention concerns levorotatory enantiomer for compound of the formula (B) and its pharmaceutically acceptable salts, where R1 is methyl, X is -COOMe; and levorotatory enantiomer for compound of the formula (B) and its pharmaceutically acceptable salts, where R1 is methyl, X is -COOEt. Additionally invention concerns methods of obtaining indicated enantiomers by asymmetrical hydration of respective source compounds in the form of Z and E isomers. ^ EFFECT: intermediary compounds for obtainment of levetiracetam medicine. ^ 4 cl, 4 tbl, 8 ex |
| 申请公布号 |
RU2355680(C2) |
申请公布日期 |
2009.05.20 |
| 申请号 |
RU20060125756 |
申请日期 |
2001.02.21 |
| 申请人 |
JUSIBI FARSHIM S.A. (AG-LTD) |
发明人 |
SARTIS DZHON;MARMON VIOLETA;DIFFERDEHN EHDMON;ZIMMERMANN VINSENT |
| 分类号 |
C07D401/04;A61K31/4015;A61K31/4025;A61K31/41;A61K31/4178;A61K31/4188;A61K31/4192;A61K31/4196;A61K31/422;A61K31/4245;A61K31/427;A61K31/433;A61K31/4439;A61K31/497;A61K31/506;A61K31/541;A61P9/00;A61P9/06;A61P9/10;A61P11/00;A61P11/06;A61P21/00;A61P25/00;A61P25/04;A61P25/06;A61P25/08;A61P25/14;A61P25/16;A61P25/20;A61P25/22;A61P25/24;A61P25/28;A61P25/30;A61P27/16;A61P37/08;C07B61/00;C07C237/06;C07C237/12;C07D207/26;C07D207/27;C07D207/273;C07D207/277;C07D307/33;C07D401/06;C07D403/04;C07D403/06;C07D403/12;C07D405/04;C07D409/04;C07D413/04;C07D417/04;C07D495/04 |
主分类号 |
C07D401/04 |
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