发明名称 |
Method for the production of proteins with chemically functionalized N-termini |
摘要 |
The present invention refers to the production of N-terminally modified polypeptides, wherein an N-terminal methionine residue is replaced by a non-genetically encoded amino acid residue. The non-genetically coded amino acid residue may comprise a functional chemical moiety for coupling two heterologous molecules, e.g. reporter or effector molecules.
|
申请公布号 |
EP2060584(A1) |
申请公布日期 |
2009.05.20 |
申请号 |
EP20070020231 |
申请日期 |
2007.10.16 |
申请人 |
MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. |
发明人 |
BUDISA, NEDILJKO;MERKEL, LARS;CHEBURKIN, YURI;ULLRICH, AXEL;KNYAZEV, PIOTR;WILTSCHI, BIRGIT |
分类号 |
C07K14/485;C07K1/107;C12P1/04 |
主分类号 |
C07K14/485 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|