发明名称 |
Imidazol-2-one compounds useful in the treatment of various disorders |
摘要 |
A compound of formula (I) wherein: R is a group selected from: A-B is a bivalent radical of formula (v), (vi) or (vii) <?in-line-formulae description="In-line Formulae" end="lead"?>-CH-C(R11)- (v)<?in-line-formulae description="In-line Formulae" end="tail"?> <?in-line-formulae description="In-line Formulae" end="lead"?>-C(R10)-CH- or (vi)<?in-line-formulae description="In-line Formulae" end="tail"?> <?in-line-formulae description="In-line Formulae" end="lead"?>-C(R12)(R10)-C(R11)(R13)- (viii)<?in-line-formulae description="In-line Formulae" end="tail"?> and all other variables are as defined herein or a pharmaceutically acceptable salt or solvate thereof, process for their preparation and their use in the treatment of conditions mediated by tachykinins and/or by selective inhibition of serotonin reuptake transporter protein.
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申请公布号 |
US7534893(B2) |
申请公布日期 |
2009.05.19 |
申请号 |
US20050570059 |
申请日期 |
2005.06.07 |
申请人 |
GLAXO GROUP LIMITED |
发明人 |
ALVARO GIUSEPPE;GHIRLANDA DAMIANO |
分类号 |
C07D405/00;A61K31/4166;C07D233/00;C07D401/04 |
主分类号 |
C07D405/00 |
代理机构 |
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