发明名称 Imidazol-2-one compounds useful in the treatment of various disorders
摘要 A compound of formula (I) wherein: R is a group selected from: A-B is a bivalent radical of formula (v), (vi) or (vii) <?in-line-formulae description="In-line Formulae" end="lead"?>-CH-C(R11)- (v)<?in-line-formulae description="In-line Formulae" end="tail"?> <?in-line-formulae description="In-line Formulae" end="lead"?>-C(R10)-CH- or (vi)<?in-line-formulae description="In-line Formulae" end="tail"?> <?in-line-formulae description="In-line Formulae" end="lead"?>-C(R12)(R10)-C(R11)(R13)- (viii)<?in-line-formulae description="In-line Formulae" end="tail"?> and all other variables are as defined herein or a pharmaceutically acceptable salt or solvate thereof, process for their preparation and their use in the treatment of conditions mediated by tachykinins and/or by selective inhibition of serotonin reuptake transporter protein.
申请公布号 US7534893(B2) 申请公布日期 2009.05.19
申请号 US20050570059 申请日期 2005.06.07
申请人 GLAXO GROUP LIMITED 发明人 ALVARO GIUSEPPE;GHIRLANDA DAMIANO
分类号 C07D405/00;A61K31/4166;C07D233/00;C07D401/04 主分类号 C07D405/00
代理机构 代理人
主权项
地址