| 发明名称 |
4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART ANDKIDNEY INSUFFICIENCY |
| 摘要 |
<p>The invention relates to novel piperidine derivatives of the general formula I (see formula I) wherein R1, R2, R3, R4, Q, W, X, Z, m and n have the meaning given in the specification. The novel piperidine derivatives can be used as renin inhibitors in the control or prevention of high blood pressure and cardiac insufficiency, as well as glaucoma, cardiac infarct, kidney insufficiency and restonosis.</p> |
| 申请公布号 |
CA2230931(C) |
申请公布日期 |
2009.05.19 |
| 申请号 |
CA19962230931 |
申请日期 |
1996.08.29 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
VIEIRA, ERIC;BUR, DANIEL;STADLER, HEINZ;BREU, VOLKER;FISCHLI, WALTER;BINGGELI, ALFRED;GULLER, ROLF;MULLER, MARCEL;HIRTH, GEORGES;OEFNER, CHRISTIAN;WOSTL, WOLFGANG;WILHELM, MAURICE;MARKI, HANS-PETER |
| 分类号 |
C07D211/18;C07D211/42;A61K31/435;A61K31/439;A61K31/4427;A61K31/443;A61K31/4433;A61K31/445;A61K31/451;A61K31/4523;A61K31/47;A61K31/495;A61K31/505;A61K31/535;A61K31/54;A61P9/00;A61P9/08;A61P9/10;A61P9/12;A61P13/02;A61P15/00;A61P27/02;C07D211/20;C07D211/22;C07D211/26;C07D211/32;C07D211/44;C07D211/54;C07D211/56;C07D211/74;C07D401/02;C07D401/04;C07D401/06;C07D401/10;C07D401/12;C07D401/14;C07D405/00;C07D405/04;C07D405/06;C07D405/12;C07D405/14;C07D409/00;C07D409/10;C07D409/12;C07D413/00;C07D413/10;C07D413/12;C07D413/14;C07D417/00;C07D417/12;C07D417/14;C07D471/08;C07D521/00;C07F7/10 |
主分类号 |
C07D211/18 |
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