发明名称 |
Preparation of pharmaceutical salts |
摘要 |
In one embodiment, the present invention discloses a process to directly prepare an unequal ratio of rotamers of an acid salt from a basic compound, by creative choice of a solvent medium. The process is particularly useful in preparing specific rotamers of pharmaceutically useful salts in desired preponderance.
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申请公布号 |
US7534884(B2) |
申请公布日期 |
2009.05.19 |
申请号 |
US20050093560 |
申请日期 |
2005.03.30 |
申请人 |
SCHERING CORPORATION |
发明人 |
GALA DINESH;GOODMAN ANDREW J.;LEE GARY;LIAO HONGBIAO;SCHWARTZ MARTIN L.;TANG SUHAN;TSAI DAVID J. S.;WU WENXUE |
分类号 |
C07D401/14;A61K31/095;A61K31/19;A61K31/194;A61K31/506;A61P1/04;A61P11/06;A61P17/00;A61P17/06;A61P19/02;A61P25/00;A61P29/00;A61P37/06;A61P37/08;A61P43/00;C07D401/06 |
主分类号 |
C07D401/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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