发明名称 |
METHODS OF ENHANCING PROTEIN INCORPORATION INTO VIRUS LIKE PARTICLES |
摘要 |
The present invention comprises a method of increasing glycoprotein incorporation on the surface of VLPs, comprising expressing a nucleic acid encoding a chimeric glycoprotein in a host cell, wherein said chimeric glycoprotein comprises the transmembrane domain of an influenza hemagglutinin protein. The invention also embodies specific VLPs comprising said chimeric glycoproteins and methods of inducing immunity in an animal utilizing said VLPs. |
申请公布号 |
WO2008005777(A3) |
申请公布日期 |
2009.05.14 |
申请号 |
WO2007US72272 |
申请日期 |
2007.06.27 |
申请人 |
NOVAVAX, INC.;SMITH, GAIL;PUSHKO, PETER |
发明人 |
SMITH, GAIL;PUSHKO, PETER |
分类号 |
C12Q1/70 |
主分类号 |
C12Q1/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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