METHOD OF DIAGNOSIS AND SUBGROUP ANALYSIS IN SUBJECTS HAVING OR BEING SUSPECTED OF HAVING IRRITABLE BOWEL SYNDROME, NUCLEIC ACIDS AND KITS, AND THEIR USE

摘要

Method of diagnosis and subgroup analysis in subjects having or being suspected of having Irritable Bowel Syndrome, nucleic acids and kits, and their use The invention relates to a method of diagnosis and subgroup analysis in subjects having or being suspected of having IrritableBowelSyndromebased on the detection of polymorphisms in serotonin type 3 receptor (5-HT3) genes. The invention relates to certain nucleic acids, in particular probes, and kits containing said nucleic acids. The methods, probes and kits are useful for diagnosing Irritable Bowel Syndrome and predicting the potential benefits of 5-HT3 receptor antagonist treatment.