发明名称 METHOD AND MEDICINE FOR INHIBITING EXPRESSION OF SPECIFIC GENE
摘要 <P>PROBLEM TO BE SOLVED: To provide a medicine containing at least one double-stranded oligoribonucleotide (dsRNA) designed to inhibit the expression of a target gene. <P>SOLUTION: One strand of the dsRNA is at least in part complementary to the target gene. The target gene can be selected from the following group: a cancer gene, a cytokine gene, an Id protein gene, a developmental gene, and a prion gene. The target gene can be expressed in a pathogenic organism (especially, Plasmodium). The target gene can also preferably be a part of a virus or viroid which is pathogenic to human. <P>COPYRIGHT: (C)2009,JPO&INPIT
申请公布号 JP2009100758(A) 申请公布日期 2009.05.14
申请号 JP20090002826 申请日期 2009.01.08
申请人 ALNYLAM EUROPE AG 发明人 KREUTZER ROLAND;LIMMER STEPHAN
分类号 C12N15/09;A61K9/127;A61K31/70;A61K31/713;A61K35/76;A61K38/00;A61K47/48;A61K48/00;A61P25/28;A61P31/12;A61P35/00;A61P43/00;C12N15/11 主分类号 C12N15/09
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