发明名称 MODULATION OF FACTOR 7 EXPRESSION
摘要 Disclosed herein are antisense compounds and methods for decreasing Factor 7 and treating or preventing thromboembolic complications, hyperproliferative disorders, or inflammatory conditions in an individual in need thereof. Examples of disease conditions that can be ameliorated with the administration of antisense compounds targeted to Factor 7 include thrombosis, embolism, and thromboembolism, such as, deep vein thrombosis, pulmonary embolism, myocardial infarction, stroke, cancer, rheumatoid arthritis, and fibrosis.
申请公布号 WO2009061851(A2) 申请公布日期 2009.05.14
申请号 WO2008US82526 申请日期 2008.11.05
申请人 ISIS PHARMACEUTICALS, INC.;FREIER, SUSAN, M.;MONIA, BRETT, P.;ZHANG, HONG;CROSBY, JEFFREY, R.;ZHAO, CHENGUANG 发明人 FREIER, SUSAN, M.;MONIA, BRETT, P.;ZHANG, HONG;CROSBY, JEFFREY, R.;ZHAO, CHENGUANG
分类号 A61K31/713;A61P7/02;A61P9/14;A61P11/00;C07H21/00;C12N15/113 主分类号 A61K31/713
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