| 发明名称 |
ANTISENSE MODULATION OF PTP1B EXPRESSION |
| 摘要 |
Compounds, compositions and methods are provided for modulating the expression of PTP1B. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding PTP1B. Methods of using these compounds for modulation of PTP1B expression and for treatment of diseases associated with expression of PTP1B are provided.
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| 申请公布号 |
US2009124009(A1) |
申请公布日期 |
2009.05.14 |
| 申请号 |
US20080046421 |
申请日期 |
2008.03.11 |
| 申请人 |
ISIS PHARMACEUTICALS, INC. |
发明人 |
BHANOT SANJAY;COWSERT LEX M.;WYATT JACQUELINE R.;MONIA BRETT P.;BUTLER MADELLINE M.;MCKAY ROBERT;FREIER SUSAN M.;DOBIE KENNETH W. |
| 分类号 |
A61K;A61K31/711;A61K38/00;A61K48/00;C07H21/04;C12N5/02;C12N15/113 |
主分类号 |
A61K |
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