发明名称 AZA SPIRO ALKANE DERIVATIVES AS INHIBITORS OF METALLOPROTEASES
摘要 The present invention provides a compound of Formula I or Formula II: enantiomer, diastereomer, prodrug, solvate, metabolite, or pharmaceutically acceptable salt thereof, wherein constituent variables are provided herein. The compounds of Formula I and II are modulators of metalloproteases and are useful in treating diseases associated with metalloprotease activity such as arthritis, cancer, cardiovascular disorders, skin disorders, inflammation and allergic conditions.
申请公布号 US2009124649(A1) 申请公布日期 2009.05.14
申请号 US20080327313 申请日期 2008.12.03
申请人 INCYTE CORPORATION 发明人 YAO WENQING;ZHUO JINCONG;XU MEIZHONG;ZHANG FENGLEI;METCALF BRIAN
分类号 A61K31/445;A61K;A61K31/4188;A61K31/424;A61K31/428;A61K31/4747;A61P9/10;A61P25/28;C07D;C07D215/06;C07D471/10;C07D491/10;C07D497/10 主分类号 A61K31/445
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