SELECTIVE RING-OPENING CROSS-METATHESIS OF CYCLOOLEFIN

摘要

PROBLEM TO BE SOLVED: To provide a catalyst for a ring-opening cross-metathsis reaction between a cycloolefinic substrate and a second olefinic reactant.

SOLUTION: The catalyst used is a transition metal alkylidene complex substituted with an N-heterocyclic carbene ligand. The substrate is selected so that the rate of the cross-metathesis reaction of the second olefinic reactant, kCM, is greater than or equal to the rate of the ring-opening metathesis reaction, kRO. In this way, the predominant ROCM product is a monomer, a dimer, and/or an oligomer, but not a polymer. The invention additionally provides for the selective production of an end-differentiated olefinic product, using trisubstituted cycloolefins as substrates and/or a subsequent cross-metathesis reaction following an initial ROCM step.

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