发明名称 |
SOME 2-PYRAZINONE DERIVATIVES AND THEIR USE AS INHIBITORS OF NEUTROPHILE ELASTASE |
摘要 |
The invention provides certain novel 6-heteroaryl-5-methyl-3- oxo-4- [3 (trif luoromethyl) phenyl] -3,4-dihydropyrazine-2- carboxamide derivatives and pharmaceutically acceptable salts thereof and particular Forms thereof; together with processes for their preparation, pharmaceutical compositions containing them and their use in therapy. The compounds are inhibitord of human neutrophil elastase.
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申请公布号 |
CA2703996(A1) |
申请公布日期 |
2009.05.14 |
申请号 |
CA20082703996 |
申请日期 |
2008.11.05 |
申请人 |
ASTRAZENECA AB |
发明人 |
AINGE, DEBRA;CHAPMAN, DAVID;LINDSJOE, MARTIN;LOENN, HANS;LUNDKVIST, MICHAEL;MUNCK AF ROSENSCHOELD, MAGNUS;NIKITIDIS, ANTONIOS;PAVEY, JOHN |
分类号 |
C07D403/04;A61K31/497;A61P1/04;A61P11/00;A61P19/00;C07D401/14 |
主分类号 |
C07D403/04 |
代理机构 |
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地址 |
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