Oral stannous compositions

摘要

The present invention relates to an aqueous oral composition comprising:
a) from 0.2% to 3% divalent metal ions comprising:
i. from 0.1% to 1.5% of zinc ions;
ii. from 0.1% to 2% oftin (II) ions; and
b) a source of fluoride ions;
c) a silica dental abrasive;
d) one or more chelants having a MW of less than 1000 and capable of forming water-soluble complexes with the zinc ions, wherein the chelants comprise less than 0.2% linear polyphosphates having a chain length of four or more;
e) an orally acceptable carrier comprising at least 20% total water;
wherein the pH of the composition is from 5 to 6.5, the molar ratio of the chelants to the divalent metal ions is at least 0.70:1 and at least 80% by weight of the total zinc ions are solubilised within the composition. The composition of the invention has been found to give improved antimicrobial activity from the zinc / stannous combination without significant taste, staining or stability problems, compared to compositions having lower levels of chelants.