<p>The present invention includes compositions and methods for delivering one or more active agents in vivo by contacting a target organ or tissue with a microbubble encapsulated active agent comprising a neutrally charged lipid microbubble loaded with cationic liposomes comprising one or more active agents and selectively releasing the active agents at the target by exposing the microbubble at the target with ultrasound, wherein the active agents remain protected in the microbubble until selectively release at the target.</p>
申请公布号
EP1793865(A4)
申请公布日期
2009.05.13
申请号
EP20050858371
申请日期
2005.08.05
申请人
BAYLOR RESEARCH INSTITUTE;BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM