发明名称 Composition Containing Stability-Improved Chloromethyl Phosphate Derivatve and Process for Producing Same
摘要 The present invention provides a production process or the like, which is a process for producing a chloromethyl phosphate derivative useful for producing a water-soluble prodrug, and which is excellent from the points of view of workability, operativity and energy saving. According to the present invention, there is provided a process for producing a composition containing a compound represented by the following Formula (I) and a tertiary amine, (wherein R1 and R2 are identical or different from each other, and represent a C1-C6 alkyl group, a C2-C6 alkenyl group or a C6-C14 aryl C1-C6 alkyl group which may have a substituent, and R1 and R2 may together form a ring), the process comprising adding the tertiary amine to the compound represented by Formula (I).
申请公布号 US2009114877(A1) 申请公布日期 2009.05.07
申请号 US20060991603 申请日期 2006.09.08
申请人 EISAI R&D MANAGEMENT CO., LTD. 发明人 NEGI SHIGETO;MIYAZAWA MAMORU
分类号 C09K3/00 主分类号 C09K3/00
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