摘要 |
The compositions and methods disclosed herein pertain to the manufacture and use of hydrogels. The disclosed compositions and methods pertain to hydrogels capable of induction by a variety of methodologies, such as by pH, salt and/or mixing. Such hydrogels are capable of self- or co-assembly and while doing so, may entrap a variety of bioactive agents in their native form, such as proteins, DNA, RNA and the like. The hydrogels of the present invention also demonstrate rapid sheer-responsiveness. The hydrogels of the present invention are biodegradable, biocompatible and useful as a biomaterial or drug-delivery device. |
申请人 |
UNIVERSITY OF UTAH RESEARCH FOUNDATION;THE JOHNS HOPKINS UNIVERSITY;YU, YIHUA, BRUCE;RAMACHANDRAN, SIVAKUMAR;FLYNN, PETER;TSENG, YIIDER |
发明人 |
YU, YIHUA, BRUCE;RAMACHANDRAN, SIVAKUMAR;FLYNN, PETER;TSENG, YIIDER |