TREATMENT OF FIBRILLINOPATHY OR ELASTINOPATHY USING GRANZYME INHIBITORS

摘要

A method of medical treatment or prevention fibrillinopathy or an elastinopathy in a subject, the method including administering a therapeutically effective amount of a granzyme B inhibitor and/or granzyme A inhibitor to the subject is provided. In other aspects uses of granzyme B and/or granzyme A inhibitors for treatment and/or prevention of a fibrillinopathy or an elastinopathy, or for preparation of medicaments for treatment of a fibrillinopathy or an elastinopathy are provided.