摘要 |
<p>Tricyclic compounds containing a cyclopropanecarboxylic acid fused to a bicyclic ring, including pharmaceutically acceptable salts, are agonists of G-protein coupled receptor 40 (GPR40) and are useful as therapeutic compounds, particularly in the treatment of Type 2 diabetes, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslipidemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia.</p> |
申请人 |
MERCK & CO., INC.;LIANG, GUI-BAI;LIAO, XIBIN;LIU, WEIGUO;FINKE, PAUL, E.;KIM, DOOSEOP;YANG, LIHU;LIN, SONGNIAN |
发明人 |
LIANG, GUI-BAI;LIAO, XIBIN;LIU, WEIGUO;FINKE, PAUL, E.;KIM, DOOSEOP;YANG, LIHU;LIN, SONGNIAN |