发明名称 ANTI-ErbB2 ANTIBODY
摘要 <P>PROBLEM TO BE SOLVED: To provide an apoptotic anti-ErbB2 antibody associated with the antibodies binding to an ErbB2 receptor. <P>SOLUTION: Provided are an anti-ErbB2 antibody binding to the domain 1 of the ErbB2 and inducing cell death through the apoptosis, an antibody binding to the epitope 7C2/7F3 on the ErbB2, a composition containing the above antibody and a pharmaceutically acceptable carrier, a nucleic acid encoding the antibody, a vector containing the nucleic acid, and host cells containing the nucleic acid. The method for preparing the anti-ErbB2 antibody comprising the recovery of the anti-ErbB2 antibody from the culture of the host cells is also provided. <P>COPYRIGHT: (C)2009,JPO&INPIT
申请公布号 JP2009095339(A) 申请公布日期 2009.05.07
申请号 JP20080233962 申请日期 2008.09.11
申请人 GENENTECH INC;BOARD OF REGENTS THE UNIV OF TEXAS SYSTEM 发明人 FENDLY BRIAN M;PHILLIPS GAIL DIANNE;SCHEUERMANN RICHARD H;UHR JONATHAN W
分类号 A61K45/00;C12N15/09;A61J1/05;A61J1/14;A61K31/131;A61K31/136;A61K31/138;A61K31/198;A61K31/255;A61K31/407;A61K31/4164;A61K31/4375;A61K31/475;A61K31/513;A61K31/519;A61K31/573;A61K31/664;A61K31/675;A61K31/704;A61K31/7048;A61K31/7068;A61K31/7135;A61K33/24;A61K38/00;A61K39/00;A61K39/395;A61K51/00;A61P35/00;A61P35/02;A61P43/00;C07K16/28;C07K16/30;C07K16/32;C12N5/10;C12N15/02;C12N15/13;C12P21/02;C12P21/08;G01N33/53;G01N33/574;G01N33/577 主分类号 A61K45/00
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