发明名称 Preventive or Therapeutic Agents for Pancreatic Cancer, Ovarian Cancer, or Liver Cancer Comprising a Novel Water-Soluble Prodrug
摘要 Preventive or therapeutic agents for pancreatic cancer, ovarian cancer, or liver cancer of the present invention comprise a water-soluble prodrug represented by formula 1 described below, or a pharmaceutically acceptable salt, or a hydrate or solvate of the prodrug or pharmaceutically acceptable salt, (wherein, R1 represents a hydrogen atom, or a C1-C6 alkyl group; W represents a divalent group comprising a tertiary amino group or a divalent group comprising a sulfonyl group, and Y represents a residue of a compound represented by Y-OH comprising an alcoholic hydroxyl group, wherein said Y-OH is a camptothecin, a taxane, or an anticancer nucleotide).
申请公布号 US2009118271(A1) 申请公布日期 2009.05.07
申请号 US20060083831 申请日期 2006.10.19
申请人 CHUGAI SEIYAKU KABUSHIKI KAISHA 发明人 UMEDA ISAO;OHWADA JUN;OZAWA SAWAKO;ENDO MIKA;URA MASAKO
分类号 A61K31/5377;A61K31/4375;A61K31/519;A61P35/00;C07D491/22 主分类号 A61K31/5377
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