发明名称 |
METHODS AND COMPOSITIONS FOR UNIVERSAL SIZE-SPECIFIC POLYMERASE CHAIN REACTION |
摘要 |
Provided herein are products and processes for the amplification, detection and sequencing of short-stranded nucleic acid in the presence of a high background of long-stranded genomic material (e.g., host or maternal nucleic acids). The methods rely on the use of inside and outside primers introduced at varying concentrations, as well as universal amplification reactions that preferentially amplify short, low copy number nucleic acid. |
申请公布号 |
WO2009032781(A3) |
申请公布日期 |
2009.05.07 |
申请号 |
WO2008US74692 |
申请日期 |
2008.08.28 |
申请人 |
SEQUENOM, INC.;LEE, MIN, SEOB;YANG, YANFENG |
发明人 |
LEE, MIN, SEOB;YANG, YANFENG |
分类号 |
C12Q1/68;C12N15/09;C12P19/34;G01N33/50 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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