TOXOPLASMA GONDII MUTANT WITH ENHANCED HOMOLOGOUS RECOMBINATION AND USES THEREOF
摘要
<p>The present invention relates to a mutant Toxoplasma gondii which exhibits enhanced homologous recombination. The mutant of the present invention is a knockout in the KU80-dependent nonhomologous end-joining pathway which finds application in generating T. gondii gene knockouts and gene replacements for use in vaccine and drug development.</p>
申请公布号
WO2009058712(A1)
申请公布日期
2009.05.07
申请号
WO2008US81274
申请日期
2008.10.27
申请人
TRUSTEES OF DARTMOUTH COLLEGE;BZIK, DAVID, J.;FOX, BARBARA, A.
