摘要 |
<p>The present invention relates to a method of isotopically labeling glycans and in facilitating high throughput quantitative/comparative analysis of glycomic compositions of biological cells. The method is applicable inter alia for identifying differentiated cells and their glycomic characteristics, differentiation conditions, disease and/or therapeutic progression, diagnosing disease states, determining drug activity, establishing manufacturing efficiencies and for determining the half-life of glycans in cells.</p> |
申请人 |
UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.;WELLS, ROBERT, LANCE;ORLANDO, RONALD, C.;DALTON, STEPHEN;MOREMEN, KELLEY, W.;PIERCE, J., MICHAEL;ATWOOD, JAMES, A.;TIEMEYER, MICHAEL;YORK, WILLIAM, S. |
发明人 |
WELLS, ROBERT, LANCE;ORLANDO, RONALD, C.;DALTON, STEPHEN;MOREMEN, KELLEY, W.;PIERCE, J., MICHAEL;ATWOOD, JAMES, A.;TIEMEYER, MICHAEL;YORK, WILLIAM, S. |