METHOD FOR CONDUCTING AN ASSAY FOR NEUTRALIZING ANTIBODIES
摘要
<p>A A method for conducting a neutralization assay for the determination of the titer of antibodies in a sample is provided which is an improvement over existing neutralization assays because the sensitivity of the reporter gene assay to determine neutralization is increased by the use of a "one time use" cell line transformed with a reporter gene construct. The titer is determined for antibodies specific for a predetermined target molecule that activates the signal transduction activity of a cell surface protein or a pattern recognition receptor or are specific for an antagonist for the predetermined target molecule.</p>
申请公布号
WO2009058884(A1)
申请公布日期
2009.05.07
申请号
WO2008US81610
申请日期
2008.10.29
申请人
LE CENTRE NATIONALE DE LA RECHERCHE SCIENTIFIQUE;NEUTEKBIO LIMITED;GERAGHTY, ERIN;TOVEY, MICHAEL;LALLEMAND, CHRISTOPHE