POLYPEPTIDES INVOLVED IN NEURONAL REGENERATION-ASSOCIATED GENE EXPRESSION
摘要
The present invention relates to methods for promoting regeneration response of peripheral and central nervous systems in mammals in need of such biological effects. The methods comprise altering the activity or steady state level of specific transcription factors that control regeneration of injured or degenerated neuronal cells. Preferably the activity or steady state level of specific transcription factors is altered by introducing nucleic acids to increase or decrease expressing of these transcription factors. These are useful in the treatment of neurodegenerative disorders.
申请公布号
CA2704314(A1)
申请公布日期
2009.05.07
申请号
CA20082704314
申请日期
2008.10.31
申请人
NEDERLANDS INSTITUUT VOOR NEUROWETENSCHAPPEN;VERENIGING VOOR CHRISTELIJK HOGER ONDERWIJS, WETENSCHAPPELIJK ONDERZOEK EN PATIENTENZORG
发明人
SMIT, AUGUST BENJAMIN;VERHAAGEN, JOOST;MAC GILLAVRY, HAROLD;VAN KESTEREN, RONALD ERNST