发明名称 |
PEG-COATED CORE-SHELL SILICA NANOPARTICLES AND METHODS OF MANUFACTURE AND USE |
摘要 |
Described herein are PEG-coated, core-shell nanoparticles, which display reduced aggregation and/or reduced non-specific or undesired attachment characteristics. These fluorescent nanoparticle include: a silica-based core having an organic functional group that includes a mercapto substitituent, an organic fluorescent compound, a silica shell; and a silane-PEG compound. The silica shell of the nanoparticle encapsulates the silica-based core and the silane-PEG compound is conjugated to the silica shell.
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申请公布号 |
WO2009029870(A3) |
申请公布日期 |
2009.05.07 |
申请号 |
WO2008US74894 |
申请日期 |
2008.08.29 |
申请人 |
HYBRID SILICA TECHNOLOGIES, INC.;WIESNER, ULRICH;OW, HOOISWENG |
发明人 |
WIESNER, ULRICH;OW, HOOISWENG |
分类号 |
C01B33/12;B32B5/16;B82B1/00;C09K11/02 |
主分类号 |
C01B33/12 |
代理机构 |
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主权项 |
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地址 |
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