A device for tissue ablation at least by high frequency energy comprising at least one group of probes. Each group includes a couple of high frequency probes having a single pole and being adapted for individual disposition of the pole adjacent the tissue at a desired distance from the pole of the other probe, the poles constituting a dipole adapted to apply the energy to a first volume of the tissue. The device further comprises at least one cryo probe having a cryo tip and is adapted for the disposition of the cryo tip between the poles, for cooling the tissue, inducing ablation of a second volume of the tissue which is greater than the first volume.