| 发明名称 |
Truncated EGF Receptor |
| 摘要 |
The present invention relates to truncated EGF receptor molecules that exhibit increased binding affinities for EGFR ligands such as EGF and TGF1. The present invention also relates to methods of screening for EGF receptor ligands and methods of treatment which involve the use of these molecules.
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| 申请公布号 |
US2009117134(A1) |
申请公布日期 |
2009.05.07 |
| 申请号 |
US20080254655 |
申请日期 |
2008.10.20 |
| 申请人 |
COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION;LUDWIG INSTITUTE FOR CANCER RESEARCH |
发明人 |
WARD COLIN WESLEY;MCKERN NEIL MORETON;LOVRECZ GEORGE OSCAR;JORISSEN ROBERT NICHOLAS;GARRETT THOMAS PETER JOHN;ELLEMAN THOMAS CHARLES;BURGESS ANTHONY WILKES;ADAMS TIMOTHY EDWARD;DOMAGALA TERESA ANNE;NICE EDOUARD |
| 分类号 |
A61K39/395;C12N15/09;A61K38/17;A61K38/22;A61P17/06;A61P35/00;A61P43/00;C07K14/71;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/12;C12P21/02;C12Q1/02 |
主分类号 |
A61K39/395 |
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