摘要 |
Riboswitches are targets for antibiotics and other small molecule therapies. Riboswitches and portions thereof can be used to regulate the expression or function of RNA molecules and other elements and molecules. Riboswitches and portions thereof can be used in a variety of other methods to, for example, identify or detect compounds. Compounds can be used to stimulate, active, inhibit and/or inactivate the riboswitch. Riboswitches and portions thereof, both alone and in combination with other nucleic acids, can be used in a variety of constructs and RNA molecules and can be encoded by nucleic acids. |
申请人 |
YALE UNIVERSITY;BREAKER, RONALD, R.;WEINBERG, ZASHA;SUDARSAN, NARASIMHAN;WANG, JOY, XIN;MEYER, MICHELLE, M.;ROTH, ADAM;REGULSKI, ELIZABETH, E. |
发明人 |
BREAKER, RONALD, R.;WEINBERG, ZASHA;SUDARSAN, NARASIMHAN;WANG, JOY, XIN;MEYER, MICHELLE, M.;ROTH, ADAM;REGULSKI, ELIZABETH, E. |