发明名称 |
PYRIMIDINE DERIVATIVES 934 |
摘要 |
A compound of formula (I) where one of A1,A2 or A3 is N, and the others are independently selected from CH or N; ring B is a fused 5 or 6-membered carbocyclic or heterocyclic ring which is optionally substituted as defined in the specification, and R1, R2, R3, R4, and n are as defined in the specification. The compounds are inhibitors of EphB4 orEphA2 and therefore may be useful in pharmaceutical compositions for the treatment of conditions such as cancer. |
申请公布号 |
WO2009010789(A3) |
申请公布日期 |
2009.05.07 |
申请号 |
WO2008GB50562 |
申请日期 |
2008.07.14 |
申请人 |
ASTRAZENECA AB;ASTRAZENECA UK LIMITED;BARLAAM, BERNARD, CHRISTOPHE;DUCRAY, RICHARD;KETTLE, JASON, GRANT |
发明人 |
BARLAAM, BERNARD, CHRISTOPHE;DUCRAY, RICHARD;KETTLE, JASON, GRANT |
分类号 |
C07D401/14;A61K31/506;A61P35/00;C07D405/14 |
主分类号 |
C07D401/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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