CRYSTALLINE PHOSPHATASE AND METHOD FOR USE THEREOF

摘要

This disclosure is directed to a crystalline form of a human protein tyrosine phosphatase designated cdcl4A and more particularly to a crystal of human cdcl4A, a method of crystallization thereof, and its structure, obtained by x-ray diffraction. In addition, the disclosure relates to methods of identifying new PTP binding agents and more particularly cdcl4 (A or B) substrates and inhibitors.