发明名称 |
METHOD FOR INHIBITING THE DEVELOPMENT OF TERATOMA |
摘要 |
The present invention provides a method for suppressing generation of a teratoma of an undifferentiated cell, preferably an ES cell. A biological material obtainable by the method and a therapeutic method for transplanting the biological material into a subject are also provided. An undifferentiated cell, in particular, preferably an ES cell is cultured to produce an increased embryoid body-like and the embryoid body-like is cultured for at least one week on, and adhered to, a three-dimensional solid type-I collagen carrier or an analogue thereof. Furthermore, a biological material is obtained thereby and the biological material is transplanted into a mammalian subject.
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申请公布号 |
EP2055772(A1) |
申请公布日期 |
2009.05.06 |
申请号 |
EP20070806111 |
申请日期 |
2007.08.27 |
申请人 |
MATSUMOTO DENTAL UNIVERSITY |
发明人 |
YAMAKI, MARIKO;OZAWA, HIDEHIRO;EBINA, SATOSHI;ASASHIMA, MAKOTO |
分类号 |
A61L27/00;C12N5/073;C12N5/0735 |
主分类号 |
A61L27/00 |
代理机构 |
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地址 |
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