发明名称 Deoxynojirimycin analogues and their uses as glucosylceramidase inhibitors
摘要 The invention provides a new class of deoxynojirimycin analogues, or pharmaceutically acceptable salts thereof which can suitably be used for the treatment of a disease selected from the group consisting of insulin resistance, Gauger disease, inflammatory diseases, hyperpigmentation and/or inflammatory skin conditions, overweight and obesity, lysosomal storage disorders, fungal diseases, melanoma and other tumors, and microbacterial infections. The invention further provides a pharmaceutical composition comprising said deoxynojirimycon analogue, or pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier.
申请公布号 US7528153(B2) 申请公布日期 2009.05.05
申请号 US20040595589 申请日期 2004.10.29
申请人 GENZYME CORPORATION 发明人 AERTS JOHANNES MARIA FRANCISCUS GERARDUS
分类号 A61K31/445;C07D211/06;C07D211/46;C07D401/00 主分类号 A61K31/445
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