发明名称 Prolinamide derivatives as NK3 antagonists
摘要 The present invention relates to a compound of formula I wherein R1, R2, R3, R4, R5, X, n, and o are as defined herein and to a pharmaceutically acceptable acid addition salt thereof which are high potential NK-3 receptor antagonists for the treatment of depression, pain, psychosis, Parkinson's disease, schizophrenia, anxiety and attention deficit hyperactivity disorder (ADHD).
申请公布号 US7528136(B2) 申请公布日期 2009.05.05
申请号 US20080129718 申请日期 2008.05.30
申请人 HOFFMANN-LA ROCHE INC. 发明人 HAN BO;KNUST HENNER;NETTEKOVEN MATTHIAS;RATNI HASANE;WU XIHAN
分类号 A61K31/496;A61K31/401;A61K31/4725;C07D207/16;C07D401/06;C07D487/10 主分类号 A61K31/496
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