| 发明名称 |
Monoclonal antibodies that recognize a shared epitope between the human immunodeficiency virus type 1 (HIV-1) capsid (CA/p24) and the human immunodeficiency virus type 2 (HIV-2) capsid (CA/p26) |
| 摘要 |
The present invention relates to novel monoclonal antibodies which may be used in the detection of Human Immunodeficiency Virus (HIV). These antibodies exhibit an unusually high degree of sensitivity, a remarkably broad range of specificity, and bind to novel shared, non-cross-reactive epitopes. In particular, the monoclonal antibodies of the present invention may be utilized to detect HIV-1 antigen and HIV-2 core antigen in a patient sample.
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| 申请公布号 |
US7528238(B2) |
申请公布日期 |
2009.05.05 |
| 申请号 |
US20040940162 |
申请日期 |
2004.09.14 |
| 申请人 |
ABBOTT LABORATORIES, INC. |
发明人 |
LOU SHENG C.;HUNT JEFFREY C.;KONRATH JOHN G.;QIU XIAOXING;SCHEFFEL JAMES W.;TYNER JOAN D. |
| 分类号 |
C12P21/08;G01N33/569;C07K14/16;C07K16/10;C12N5/10;C12N5/20;C12N15/02 |
主分类号 |
C12P21/08 |
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